Drug interactions
Devil's claw + Nabumetone
Severity: Minor
Devil's claw and Nabumetone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw is used for joint pain and has been associated with bleeding in case reports, possibly through antiplatelet effects. Combined with an NSAID it provides duplicate therapy and may increase bleeding or GI risk.
What this interaction means in plain words
Devil's claw and Nabumetone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet effect; mechanism of the herb is not well established.
What to do
Discourage combined use and monitor for bleeding or dyspepsia if both are taken.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nabumetone
- Ketorolac intranasal + Nabumetone Contraindicated
- Ketorolac + Nabumetone Contraindicated
- Aceclofenac + Nabumetone Major
- Acemetacin + Nabumetone Major
- Acetylsalicylic acid + Nabumetone Major
- Alteplase + Nabumetone Major
Frequently asked questions
Can I take Devil's claw with Nabumetone?
MediHelp rates the interaction as minor. Devil's claw and Nabumetone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw is used for joint pain and has been associated with bleeding in case reports, possibly through antiplatelet effects. Combined with an NSAID it provides duplicate therapy and may increase bleeding or GI risk.
How serious is the interaction between Devil's claw and Nabumetone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Discourage combined use and monitor for bleeding or dyspepsia if both are taken.
What other medicines interact with Nabumetone?
MediHelp also lists interactions of Nabumetone with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Nabumetone page.
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