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Drug interactions

Devil's claw + Omeprazole

Severity: Minor

Devil's claw and Omeprazole: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Devil's claw may stimulate gastric acid secretion, which could theoretically reduce the effect of acid suppressants. Clinical evidence is lacking.

What this interaction means in plain words

Devil's claw and Omeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical opposition through increased gastric acid secretion; not established.

What to do

No specific action is needed beyond awareness. If symptoms persist, consider stopping the herbal product.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Devil's claw with Omeprazole?

MediHelp rates the interaction as minor. Devil's claw and Omeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw may stimulate gastric acid secretion, which could theoretically reduce the effect of acid suppressants. Clinical evidence is lacking.

How serious is the interaction between Devil's claw and Omeprazole?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond awareness. If symptoms persist, consider stopping the herbal product.

What other medicines interact with Omeprazole?

MediHelp also lists interactions of Omeprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Omeprazole page.

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