Drug interactions
Dexamethasone-tobramycin + Lasmiditan
Severity: Minor
Dexamethasone-tobramycin and Lasmiditan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan inhibits P-glycoprotein in vitro and could raise exposure to P-gp substrates such as dexamethasone. The clinical significance is uncertain and likely small, especially with topical or ophthalmic dexamethasone.
What this interaction means in plain words
Dexamethasone-tobramycin and Lasmiditan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dexamethasone-tobramycin belongs to Anti Bacterial; Lasmiditan belongs to Central Nervous System.
Why it happens
Lasmiditan may inhibit P-glycoprotein efflux of dexamethasone.
What to do
No specific action is needed; monitor for corticosteroid adverse effects if systemic dexamethasone is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dexamethasone-tobramycin
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Dexamethasone-tobramycin with Lasmiditan?
MediHelp rates the interaction as minor. Dexamethasone-tobramycin and Lasmiditan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lasmiditan inhibits P-glycoprotein in vitro and could raise exposure to P-gp substrates such as dexamethasone. The clinical significance is uncertain and likely small, especially with topical or ophthalmic dexamethasone.
How serious is the interaction between Dexamethasone-tobramycin and Lasmiditan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; monitor for corticosteroid adverse effects if systemic dexamethasone is used.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
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