Drug interactions
Dexfenfluramine + Hydromorphone
Severity: Minor
Dexfenfluramine and Hydromorphone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dexfenfluramine is a serotonergic anorectic, withdrawn from the market, with no well-documented interaction with hydromorphone. Any effect on sedation is uncertain.
What this interaction means in plain words
Dexfenfluramine and Hydromorphone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism; the effect on sedation is uncertain.
What to do
No specific action required beyond routine monitoring of sedation and respiratory status.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydromorphone
- Alvimopan + Hydromorphone Contraindicated
- Bupropion-naltrexone + Hydromorphone Contraindicated
- Hydromorphone + Isocarboxazid Contraindicated
- Hydromorphone + Olanzapine / samidorphan Contraindicated
- Hydromorphone + Phenelzine Contraindicated
- Hydromorphone + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Dexfenfluramine with Hydromorphone?
MediHelp rates the interaction as minor. Dexfenfluramine and Hydromorphone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dexfenfluramine is a serotonergic anorectic, withdrawn from the market, with no well-documented interaction with hydromorphone. Any effect on sedation is uncertain.
How serious is the interaction between Dexfenfluramine and Hydromorphone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action required beyond routine monitoring of sedation and respiratory status.
What other medicines interact with Hydromorphone?
MediHelp also lists interactions of Hydromorphone with, for example, Alvimopan, Bupropion-naltrexone, Isocarboxazid. The full list is on the Hydromorphone page.
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