Drug interactions
Dextroamphetamine + Nabilone
Severity: Moderate
Dextroamphetamine and Nabilone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nabilone is sedating while dextroamphetamine is stimulating, so their effects on alertness may partly offset one another. Both raise heart rate, so the cardiovascular effects, including tachycardia, may be additive, and nabilone can add to psychiatric effects such as anxiety or agitation.
What this interaction means in plain words
Dextroamphetamine and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dextroamphetamine belongs to Central Nervous System; Nabilone belongs to Gastrointestinal Tract.
Why it happens
Opposing CNS effects with additive sympathomimetic cardiovascular stimulation; the net effect is variable.
What to do
Monitor heart rate, blood pressure and mood or anxiety symptoms. Do not rely on one drug to counteract the effects of the other.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabilone
Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Nabilone?
MediHelp rates the interaction as moderate. Dextroamphetamine and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nabilone is sedating while dextroamphetamine is stimulating, so their effects on alertness may partly offset one another. Both raise heart rate, so the cardiovascular effects, including tachycardia, may be additive, and nabilone can add to psychiatric effects such as anxiety or agitation.
How serious is the interaction between Dextroamphetamine and Nabilone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and mood or anxiety symptoms. Do not rely on one drug to counteract the effects of the other.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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