Drug interactions
Dextroamphetamine + Temazepam
Severity: Minor
Dextroamphetamine and Temazepam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dextroamphetamine may partly offset the sedation of temazepam, but it does not reliably reverse impairment. Patients may feel more alert than their psychomotor performance warrants, and the stimulant can disturb sleep, undermining the hypnotic.
What this interaction means in plain words
Dextroamphetamine and Temazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dextroamphetamine belongs to Central Nervous System; Temazepam belongs to Central Nervous System.
Why it happens
Opposing CNS stimulant and GABA-A mediated depressant effects; no established pharmacokinetic interaction.
What to do
Reassess the need for both drugs if insomnia persists. Advise patients not to rely on perceived alertness when driving.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Other interactions of Temazepam
- Alprazolam + Temazepam Major
- Amobarbital + Temazepam Major
- Buprenorphine + Temazepam Major
- Butorphanol + Temazepam Major
- Carisoprodol + Temazepam Major
- Chloral hydrate + Temazepam Major
Frequently asked questions
Can I take Dextroamphetamine with Temazepam?
MediHelp rates the interaction as minor. Dextroamphetamine and Temazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dextroamphetamine may partly offset the sedation of temazepam, but it does not reliably reverse impairment. Patients may feel more alert than their psychomotor performance warrants, and the stimulant can disturb sleep, undermining the hypnotic.
How serious is the interaction between Dextroamphetamine and Temazepam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reassess the need for both drugs if insomnia persists. Advise patients not to rely on perceived alertness when driving.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
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