Drug interactions
Diclofenac + Terazosin
Severity: Minor
Diclofenac and Terazosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Diclofenac may reduce the blood pressure lowering effect of terazosin, mainly with sustained use. The clinical impact is usually small but can matter in patients with poorly controlled hypertension.
What this interaction means in plain words
Diclofenac and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Diclofenac belongs to Musculoskeletal; Terazosin belongs to Genitourinary.
Why it happens
NSAID inhibition of prostaglandin synthesis leads to sodium and water retention and attenuates antihypertensive effects.
What to do
Monitor blood pressure when diclofenac is started or used regularly. Use the lowest effective dose for the shortest time.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Other interactions of Diclofenac
- Diclofenac + Ketorolac Contraindicated
- Diclofenac + Ketorolac intranasal Contraindicated
- Aceclofenac + Diclofenac Major
- Acemetacin + Diclofenac Major
- Alteplase + Diclofenac Major
- Amiloride + Diclofenac Major
Frequently asked questions
Can I take Diclofenac with Terazosin?
MediHelp rates the interaction as minor. Diclofenac and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Diclofenac may reduce the blood pressure lowering effect of terazosin, mainly with sustained use. The clinical impact is usually small but can matter in patients with poorly controlled hypertension.
How serious is the interaction between Diclofenac and Terazosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when diclofenac is started or used regularly. Use the lowest effective dose for the shortest time.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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