Drug interactions
Dicloxacillin + Willow bark
Severity: Minor
Dicloxacillin and Willow bark: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Willow bark contains salicin, converted to salicylic acid, which may reduce renal secretion of penicillins. Any rise in dicloxacillin exposure is probably small.
What this interaction means in plain words
Dicloxacillin and Willow bark have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Salicylate competition for renal tubular secretion.
What to do
No routine action is needed; be aware of additive bleeding tendency with salicylates in patients with other risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dicloxacillin
- Dicloxacillin + Phenindione Major
- Atogepant + Dicloxacillin Moderate
- Axitinib + Dicloxacillin Moderate
- Bcg vaccine live + Dicloxacillin Moderate
- Cholera vaccine + Dicloxacillin Moderate
- Demeclocycline + Dicloxacillin Moderate
Frequently asked questions
Can I take Dicloxacillin with Willow bark?
MediHelp rates the interaction as minor. Dicloxacillin and Willow bark have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Willow bark contains salicin, converted to salicylic acid, which may reduce renal secretion of penicillins. Any rise in dicloxacillin exposure is probably small.
How serious is the interaction between Dicloxacillin and Willow bark?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; be aware of additive bleeding tendency with salicylates in patients with other risk factors.
What other medicines interact with Dicloxacillin?
MediHelp also lists interactions of Dicloxacillin with, for example, Phenindione, Atogepant, Axitinib. The full list is on the Dicloxacillin page.
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