Drug interactions
Atogepant + Dicloxacillin
Severity: Moderate
Atogepant and Dicloxacillin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dicloxacillin is a weak to moderate CYP3A4 inducer and may lower atogepant exposure, possibly reducing migraine prevention efficacy.
What this interaction means in plain words
Atogepant and Dicloxacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atogepant belongs to Central Nervous System; Dicloxacillin belongs to Anti Bacterial.
Why it happens
Induction of CYP3A4 increases atogepant metabolism.
What to do
Monitor migraine control during and after the antibiotic course; the effect is likely temporary, so dose changes are usually unnecessary for short courses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dicloxacillin
- Dicloxacillin + Phenindione Major
- Axitinib + Dicloxacillin Moderate
- Bcg vaccine live + Dicloxacillin Moderate
- Cholera vaccine + Dicloxacillin Moderate
- Demeclocycline + Dicloxacillin Moderate
- Dicloxacillin + Doxycycline Moderate
Other interactions of Atogepant
- Amobarbital + Atogepant Moderate
- Apalutamide + Atogepant Moderate
- Aprepitant + Atogepant Moderate
- Armodafinil + Atogepant Moderate
- Atogepant + Bosentan Moderate
- Atogepant + Carbamazepine Moderate
Frequently asked questions
Can I take Atogepant with Dicloxacillin?
MediHelp rates the interaction as moderate. Atogepant and Dicloxacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dicloxacillin is a weak to moderate CYP3A4 inducer and may lower atogepant exposure, possibly reducing migraine prevention efficacy.
How serious is the interaction between Atogepant and Dicloxacillin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor migraine control during and after the antibiotic course; the effect is likely temporary, so dose changes are usually unnecessary for short courses.
What other medicines interact with Dicloxacillin?
MediHelp also lists interactions of Dicloxacillin with, for example, Phenindione, Axitinib, Bcg vaccine live. The full list is on the Dicloxacillin page.
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