Drug interactions
Dicyclomine + Echothiophate iodide
Severity: Minor
Dicyclomine and Echothiophate iodide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Echothiophate is a cholinesterase inhibitor used in the eye, whereas dicyclomine is an antimuscarinic. Their actions oppose each other, but ophthalmic echothiophate has limited systemic exposure, so the effect is usually small.
What this interaction means in plain words
Dicyclomine and Echothiophate iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Pharmacodynamic antagonism between cholinesterase inhibition and muscarinic blockade.
What to do
Monitor for reduced effect of either drug. No dose change is normally needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dicyclomine
- Clozapine + Dicyclomine Major
- Dicyclomine + Henbane Major
- Dicyclomine + Imipramine Major
- Dicyclomine + Pramlintide Major
- Abobotulinumtoxina + Dicyclomine Moderate
- Aclidinium + Dicyclomine Moderate
Frequently asked questions
Can I take Dicyclomine with Echothiophate iodide?
MediHelp rates the interaction as minor. Dicyclomine and Echothiophate iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Echothiophate is a cholinesterase inhibitor used in the eye, whereas dicyclomine is an antimuscarinic. Their actions oppose each other, but ophthalmic echothiophate has limited systemic exposure, so the effect is usually small.
How serious is the interaction between Dicyclomine and Echothiophate iodide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced effect of either drug. No dose change is normally needed.
What other medicines interact with Dicyclomine?
MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.
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