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Drug interactions

Dicyclomine + Glucagon intranasal

Severity: Moderate

Dicyclomine and Glucagon intranasal: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Anticholinergics such as dicyclomine can add to the gastrointestinal motility inhibition produced by glucagon. This may increase the risk of gastrointestinal adverse effects such as nausea, constipation or ileus.

What this interaction means in plain words

Dicyclomine and Glucagon intranasal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive inhibition of gastrointestinal motility from anticholinergic action and glucagon.

What to do

Monitor for abdominal distension, constipation and worsening GI symptoms. Glucagon use in hypoglycemia should not be withheld.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dicyclomine with Glucagon intranasal?

MediHelp rates the interaction as moderate. Dicyclomine and Glucagon intranasal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anticholinergics such as dicyclomine can add to the gastrointestinal motility inhibition produced by glucagon. This may increase the risk of gastrointestinal adverse effects such as nausea, constipation or ileus.

How serious is the interaction between Dicyclomine and Glucagon intranasal?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for abdominal distension, constipation and worsening GI symptoms. Glucagon use in hypoglycemia should not be withheld.

What other medicines interact with Dicyclomine?

MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.

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