Drug interactions
Diethylpropion + Nabilone
Severity: Minor
Diethylpropion and Nabilone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nabilone is sedating and can cause tachycardia and mood disturbance, whereas diethylpropion is a sympathomimetic anorectic with stimulant properties. Their effects may partly oppose each other, but additive tachycardia, anxiety or agitation may occur.
What this interaction means in plain words
Diethylpropion and Nabilone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing CNS effects and possible additive sympathomimetic cardiovascular effects; no established pharmacokinetic mechanism.
What to do
Monitor heart rate, blood pressure and psychiatric symptoms when the combination is started. Reduce the dose of either drug if palpitations or agitation develop.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nabilone
Frequently asked questions
Can I take Diethylpropion with Nabilone?
MediHelp rates the interaction as minor. Diethylpropion and Nabilone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nabilone is sedating and can cause tachycardia and mood disturbance, whereas diethylpropion is a sympathomimetic anorectic with stimulant properties. Their effects may partly oppose each other, but additive tachycardia, anxiety or agitation may occur.
How serious is the interaction between Diethylpropion and Nabilone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and psychiatric symptoms when the combination is started. Reduce the dose of either drug if palpitations or agitation develop.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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