Drug interactions
Diflunisal + Measles mumps and rubella vaccine
Severity: Minor
Diflunisal and Measles mumps and rubella vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Diflunisal is a salicylate derivative, and salicylates after varicella-containing vaccines raise concern about Reye syndrome. With MMR alone, the risk is theoretical.
What this interaction means in plain words
Diflunisal and Measles mumps and rubella vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Diflunisal belongs to Musculoskeletal; Measles mumps and rubella vaccine belongs to Miscellaneous.
Why it happens
Theoretical salicylate-associated Reye syndrome; not established for MMR without varicella.
What to do
No special action for MMR alone; if a varicella-containing vaccine is given, avoid salicylates for the labeled period.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
Other interactions of Diflunisal
- Diflunisal + Ketorolac Contraindicated
- Diflunisal + Ketorolac intranasal Contraindicated
- Acemetacin + Diflunisal Major
- Acetazolamide + Diflunisal Major
- Alteplase + Diflunisal Major
- Amiloride + Diflunisal Major
Frequently asked questions
Can I take Diflunisal with Measles mumps and rubella vaccine?
MediHelp rates the interaction as minor. Diflunisal and Measles mumps and rubella vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Diflunisal is a salicylate derivative, and salicylates after varicella-containing vaccines raise concern about Reye syndrome. With MMR alone, the risk is theoretical.
How serious is the interaction between Diflunisal and Measles mumps and rubella vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No special action for MMR alone; if a varicella-containing vaccine is given, avoid salicylates for the labeled period.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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