Drug interactions
Diphenoxylate-atropine + Levetiracetam
Severity: Minor
Diphenoxylate-atropine and Levetiracetam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can cause drowsiness and dizziness, so taking them together may increase somnolence and impair psychomotor performance. The effect is generally modest at usual doses of diphenoxylate-atropine.
What this interaction means in plain words
Diphenoxylate-atropine and Levetiracetam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Diphenoxylate-atropine belongs to Gastrointestinal Tract; Levetiracetam belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects.
What to do
Counsel patients about drowsiness and caution when driving or operating machinery; no dose change is usually required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Diphenoxylate-atropine and Levetiracetam, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Diphenoxylate-atropine
- Diphenoxylate-atropine + Isocarboxazid Contraindicated
- Diphenoxylate-atropine + Phenelzine Contraindicated
- Diphenoxylate-atropine + Tranylcypromine Contraindicated
- Alfentanil + Diphenoxylate-atropine Major
- Alvimopan + Diphenoxylate-atropine Major
- Amitriptyline + Diphenoxylate-atropine Major
Other interactions of Levetiracetam
Frequently asked questions
Can I take Diphenoxylate-atropine with Levetiracetam?
MediHelp rates the interaction as minor. Diphenoxylate-atropine and Levetiracetam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both agents can cause drowsiness and dizziness, so taking them together may increase somnolence and impair psychomotor performance. The effect is generally modest at usual doses of diphenoxylate-atropine.
How serious is the interaction between Diphenoxylate-atropine and Levetiracetam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about drowsiness and caution when driving or operating machinery; no dose change is usually required.
What other medicines interact with Diphenoxylate-atropine?
MediHelp also lists interactions of Diphenoxylate-atropine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Diphenoxylate-atropine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
