Drug interactions
Dipyridamole + Duvelisib
Severity: Minor
Dipyridamole and Duvelisib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dipyridamole can inhibit the BCRP efflux transporter, and duvelisib is a BCRP substrate. Higher duvelisib exposure could increase adverse effects such as diarrhea, infection, rash and transaminase elevation. The clinical significance is predicted rather than well documented.
What this interaction means in plain words
Dipyridamole and Duvelisib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dipyridamole belongs to Cardiovascular; Duvelisib belongs to Oncology.
Why it happens
Inhibition of BCRP-mediated efflux by dipyridamole may raise duvelisib absorption and systemic exposure.
What to do
No empirical dose change is needed; monitor for duvelisib toxicity such as diarrhea, rash and liver enzyme elevation if both drugs are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Dipyridamole and Duvelisib, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Duvelisib
- Duvelisib + Ergotamine Contraindicated
- Alfuzosin + Duvelisib Major
- Apalutamide + Duvelisib Major
- Avanafil + Duvelisib Major
- Carbamazepine + Duvelisib Major
- Chloramphenicol + Duvelisib Major
Frequently asked questions
Can I take Dipyridamole with Duvelisib?
MediHelp rates the interaction as minor. Dipyridamole and Duvelisib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dipyridamole can inhibit the BCRP efflux transporter, and duvelisib is a BCRP substrate. Higher duvelisib exposure could increase adverse effects such as diarrhea, infection, rash and transaminase elevation. The clinical significance is predicted rather than well documented.
How serious is the interaction between Dipyridamole and Duvelisib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empirical dose change is needed; monitor for duvelisib toxicity such as diarrhea, rash and liver enzyme elevation if both drugs are used.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
