Drug interactions
Dipyridamole + Fostemsavir
Severity: Minor
Dipyridamole and Fostemsavir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fostemsavir's active metabolite temsavir inhibits BCRP, which may raise levels of BCRP substrates. Dipyridamole exposure could increase, with more vasodilatory adverse effects.
What this interaction means in plain words
Dipyridamole and Fostemsavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dipyridamole belongs to Cardiovascular; Fostemsavir belongs to Anti Virals.
Why it happens
BCRP inhibition by temsavir, reducing efflux of substrates.
What to do
Monitor blood pressure and tolerability. Reduce the dipyridamole dose if adverse effects occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Fostemsavir
- Apalutamide + Fostemsavir Contraindicated
- Carbamazepine + Fostemsavir Contraindicated
- Enzalutamide + Fostemsavir Contraindicated
- Fostemsavir + Mitotane Contraindicated
- Fostemsavir + Phenytoin Contraindicated
- Fostemsavir + Rifampicin Contraindicated
Frequently asked questions
Can I take Dipyridamole with Fostemsavir?
MediHelp rates the interaction as minor. Dipyridamole and Fostemsavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fostemsavir's active metabolite temsavir inhibits BCRP, which may raise levels of BCRP substrates. Dipyridamole exposure could increase, with more vasodilatory adverse effects.
How serious is the interaction between Dipyridamole and Fostemsavir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and tolerability. Reduce the dipyridamole dose if adverse effects occur.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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