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Drug interactions

Dipyridamole + Leniolisib

Severity: Minor

Dipyridamole and Leniolisib: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Leniolisib inhibits BCRP and could increase exposure to BCRP substrates. Dipyridamole's clinical sensitivity to this is uncertain and the effect is probably minor.

What this interaction means in plain words

Dipyridamole and Leniolisib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Dipyridamole belongs to Cardiovascular; Leniolisib belongs to Miscellaneous.

Evidence level: Low

Why it happens

Leniolisib inhibits BCRP, potentially reducing efflux of dipyridamole.

What to do

No routine action is needed; be aware of possible enhanced dipyridamole effects such as headache or hypotension.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dipyridamole with Leniolisib?

MediHelp rates the interaction as minor. Dipyridamole and Leniolisib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Leniolisib inhibits BCRP and could increase exposure to BCRP substrates. Dipyridamole's clinical sensitivity to this is uncertain and the effect is probably minor.

How serious is the interaction between Dipyridamole and Leniolisib?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; be aware of possible enhanced dipyridamole effects such as headache or hypotension.

What other medicines interact with Dipyridamole?

MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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