Drug interactions
Dipyridamole + Nebivolol
Severity: Minor
Dipyridamole and Nebivolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dipyridamole increases extracellular adenosine, which can slow sinus and AV nodal function. With nebivolol, bradycardia may be more likely, although clinically significant events are uncommon with oral dipyridamole.
What this interaction means in plain words
Dipyridamole and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dipyridamole belongs to Cardiovascular; Nebivolol belongs to Cardiovascular.
Why it happens
Additive negative chronotropic and dromotropic effects from raised adenosine levels and beta-1 blockade.
What to do
Monitor heart rate in patients with conduction disease or baseline bradycardia. Pay closer attention when intravenous dipyridamole is used for stress testing.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Frequently asked questions
Can I take Dipyridamole with Nebivolol?
MediHelp rates the interaction as minor. Dipyridamole and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dipyridamole increases extracellular adenosine, which can slow sinus and AV nodal function. With nebivolol, bradycardia may be more likely, although clinically significant events are uncommon with oral dipyridamole.
How serious is the interaction between Dipyridamole and Nebivolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate in patients with conduction disease or baseline bradycardia. Pay closer attention when intravenous dipyridamole is used for stress testing.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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