Drug interactions
Dong quai + Fondaparinux
Severity: Moderate
Dong quai and Fondaparinux: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin-type constituents and has been linked to antiplatelet effects and raised INR with warfarin. With fondaparinux an additive bleeding risk is theoretically possible.
What this interaction means in plain words
Dong quai and Fondaparinux can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive effects from coumarin-like constituents and platelet inhibition; the mechanism is not well established.
What to do
Advise patients to avoid dong quai during fondaparinux therapy and monitor for bleeding.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Dong quai and Fondaparinux, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Fondaparinux
- Defibrotide + Fondaparinux Contraindicated
- Fondaparinux + Ketorolac Contraindicated
- Abciximab + Fondaparinux Major
- Aceclofenac + Fondaparinux Major
- Acetylsalicylic acid + Fondaparinux Major
- Alteplase + Fondaparinux Major
Frequently asked questions
Can I take Dong quai with Fondaparinux?
MediHelp rates the interaction as moderate. Dong quai and Fondaparinux can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin-type constituents and has been linked to antiplatelet effects and raised INR with warfarin. With fondaparinux an additive bleeding risk is theoretically possible.
How serious is the interaction between Dong quai and Fondaparinux?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid dong quai during fondaparinux therapy and monitor for bleeding.
What other medicines interact with Fondaparinux?
MediHelp also lists interactions of Fondaparinux with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Fondaparinux page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
