Drug interactions
Dong quai + Mefenamic acid
Severity: Minor
Dong quai and Mefenamic acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin constituents and has been associated with increased INR and bleeding with warfarin. An additive bleeding tendency with NSAIDs is plausible but poorly documented.
What this interaction means in plain words
Dong quai and Mefenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet or coumarin-type anticoagulant effect; not well characterized.
What to do
Advise patients to report bruising or bleeding, and avoid dong quai if they also take anticoagulants.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mefenamic acid
- Ketorolac intranasal + Mefenamic acid Contraindicated
- Ketorolac + Mefenamic acid Contraindicated
- Aceclofenac + Mefenamic acid Major
- Acemetacin + Mefenamic acid Major
- Acetylsalicylic acid + Mefenamic acid Major
- Alteplase + Mefenamic acid Major
Frequently asked questions
Can I take Dong quai with Mefenamic acid?
MediHelp rates the interaction as minor. Dong quai and Mefenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dong quai contains coumarin constituents and has been associated with increased INR and bleeding with warfarin. An additive bleeding tendency with NSAIDs is plausible but poorly documented.
How serious is the interaction between Dong quai and Mefenamic acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report bruising or bleeding, and avoid dong quai if they also take anticoagulants.
What other medicines interact with Mefenamic acid?
MediHelp also lists interactions of Mefenamic acid with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Mefenamic acid page.
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