Drug interactions
Dong quai + Nabumetone
Severity: Moderate
Dong quai and Nabumetone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin-type constituents and may have antiplatelet activity, so it could add to the bleeding tendency of an NSAID. Evidence consists mainly of case reports and theory.
What this interaction means in plain words
Dong quai and Nabumetone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive antiplatelet or coumarin-like effects combined with NSAID platelet inhibition and mucosal injury.
What to do
Advise patients to avoid dong quai while taking nabumetone, or monitor for bruising and gastrointestinal bleeding. Stop the herb before planned surgery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabumetone
- Ketorolac intranasal + Nabumetone Contraindicated
- Ketorolac + Nabumetone Contraindicated
- Aceclofenac + Nabumetone Major
- Acemetacin + Nabumetone Major
- Acetylsalicylic acid + Nabumetone Major
- Alteplase + Nabumetone Major
Frequently asked questions
Can I take Dong quai with Nabumetone?
MediHelp rates the interaction as moderate. Dong quai and Nabumetone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin-type constituents and may have antiplatelet activity, so it could add to the bleeding tendency of an NSAID. Evidence consists mainly of case reports and theory.
How serious is the interaction between Dong quai and Nabumetone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid dong quai while taking nabumetone, or monitor for bruising and gastrointestinal bleeding. Stop the herb before planned surgery.
What other medicines interact with Nabumetone?
MediHelp also lists interactions of Nabumetone with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Nabumetone page.
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