Drug interactions
Doxercalciferol + Magnesium hydroxide
Severity: Minor
Doxercalciferol and Magnesium hydroxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vitamin D analogues enhance intestinal absorption of magnesium as well as calcium. In patients with renal impairment who use magnesium-containing antacids, this may contribute to hypermagnesemia.
What this interaction means in plain words
Doxercalciferol and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Active vitamin D analogues increase intestinal absorption of magnesium.
What to do
Monitor serum magnesium in patients with chronic kidney disease taking both, and avoid regular magnesium antacids if levels rise.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium hydroxide
Frequently asked questions
Can I take Doxercalciferol with Magnesium hydroxide?
MediHelp rates the interaction as minor. Doxercalciferol and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vitamin D analogues enhance intestinal absorption of magnesium as well as calcium. In patients with renal impairment who use magnesium-containing antacids, this may contribute to hypermagnesemia.
How serious is the interaction between Doxercalciferol and Magnesium hydroxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium in patients with chronic kidney disease taking both, and avoid regular magnesium antacids if levels rise.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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