Drug interactions
Doxorubicin + Mirabegron
Severity: Minor
Doxorubicin and Mirabegron: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Doxorubicin is partly metabolised by CYP2D6, but this is a minor route and clinically meaningful change from mirabegron has not been established. The expected effect is small.
What this interaction means in plain words
Doxorubicin and Mirabegron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Doxorubicin belongs to Oncology; Mirabegron belongs to Genitourinary.
Why it happens
Mirabegron weakly inhibits CYP2D6, which is a minor pathway for doxorubicin.
What to do
No routine change is needed; continue standard monitoring for doxorubicin toxicity including cardiac function and blood counts.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Doxorubicin and Mirabegron, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Mirabegron
- Digoxin + Mirabegron Major
- Flecainide + Mirabegron Major
- Mirabegron + Propafenone Major
- Mirabegron + Thioridazine Major
- Amitriptyline + Mirabegron Moderate
- Amoxapine + Mirabegron Moderate
Other interactions of Doxorubicin
Frequently asked questions
Can I take Doxorubicin with Mirabegron?
MediHelp rates the interaction as minor. Doxorubicin and Mirabegron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Doxorubicin is partly metabolised by CYP2D6, but this is a minor route and clinically meaningful change from mirabegron has not been established. The expected effect is small.
How serious is the interaction between Doxorubicin and Mirabegron?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; continue standard monitoring for doxorubicin toxicity including cardiac function and blood counts.
What other medicines interact with Mirabegron?
MediHelp also lists interactions of Mirabegron with, for example, Digoxin, Flecainide, Propafenone. The full list is on the Mirabegron page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
