Drug interactions
Doxycycline + Sucroferric oxyhydroxide
Severity: Moderate
Doxycycline and Sucroferric oxyhydroxide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iron-containing phosphate binders can bind doxycycline in the gut and reduce its absorption, which may lower antibiotic effectiveness.
What this interaction means in plain words
Doxycycline and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Doxycycline belongs to Anti Bacterial; Sucroferric oxyhydroxide belongs to Genitourinary.
Why it happens
Chelation or adsorption of doxycycline by iron in the gastrointestinal tract reduces its absorption.
What to do
Give doxycycline at least 1 hour before sucroferric oxyhydroxide. Monitor clinical response to the antibiotic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Doxycycline and Sucroferric oxyhydroxide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Doxycycline
- Acitretin + Doxycycline Contraindicated
- Aminolevulinic acid + Doxycycline Major
- Cholera vaccine + Doxycycline Major
- Doxycycline + Isotretinoin Major
- Doxycycline + Methoxyflurane Major
- Doxycycline + Microbiota Major
Other interactions of Sucroferric oxyhydroxide
Frequently asked questions
Can I take Doxycycline with Sucroferric oxyhydroxide?
MediHelp rates the interaction as moderate. Doxycycline and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron-containing phosphate binders can bind doxycycline in the gut and reduce its absorption, which may lower antibiotic effectiveness.
How serious is the interaction between Doxycycline and Sucroferric oxyhydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give doxycycline at least 1 hour before sucroferric oxyhydroxide. Monitor clinical response to the antibiotic.
What other medicines interact with Doxycycline?
MediHelp also lists interactions of Doxycycline with, for example, Acitretin, Aminolevulinic acid, Cholera vaccine. The full list is on the Doxycycline page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
