Drug interactions
Dronabinol + Sulfadiazine
Severity: Minor
Dronabinol and Sulfadiazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sulfadiazine can inhibit CYP2C9 and might slightly raise dronabinol exposure. The clinical significance is likely small.
What this interaction means in plain words
Dronabinol and Sulfadiazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Sulfadiazine weakly inhibits CYP2C9, reducing dronabinol metabolism.
What to do
No routine adjustment is needed. Monitor for increased drowsiness or dizziness if the combination is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dronabinol
- Cefotetan + Dronabinol Contraindicated
- Disulfiram + Dronabinol Contraindicated
- Dronabinol + Midazolam intranasal Major
- Dronabinol + Zuranolone Major
- Amobarbital + Dronabinol Moderate
- Apalutamide + Dronabinol Moderate
Frequently asked questions
Can I take Dronabinol with Sulfadiazine?
MediHelp rates the interaction as minor. Dronabinol and Sulfadiazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sulfadiazine can inhibit CYP2C9 and might slightly raise dronabinol exposure. The clinical significance is likely small.
How serious is the interaction between Dronabinol and Sulfadiazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor for increased drowsiness or dizziness if the combination is used.
What other medicines interact with Dronabinol?
MediHelp also lists interactions of Dronabinol with, for example, Cefotetan, Disulfiram, Midazolam intranasal. The full list is on the Dronabinol page.
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