Drug interactions
Drospirenone + Nimodipine
Severity: Minor
Drospirenone and Nimodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Drospirenone does not significantly inhibit CYP3A4, so a clinically relevant rise in nimodipine is unlikely. Any interaction is expected to be minimal.
What this interaction means in plain words
Drospirenone and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Drospirenone belongs to Endocrine; Nimodipine belongs to Cardiovascular.
Why it happens
Theoretical weak CYP3A4 effect; not established.
What to do
No adjustment is needed; monitor blood pressure routinely.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Other interactions of Drospirenone
Frequently asked questions
Can I take Drospirenone with Nimodipine?
MediHelp rates the interaction as minor. Drospirenone and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Drospirenone does not significantly inhibit CYP3A4, so a clinically relevant rise in nimodipine is unlikely. Any interaction is expected to be minimal.
How serious is the interaction between Drospirenone and Nimodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No adjustment is needed; monitor blood pressure routinely.
What other medicines interact with Nimodipine?
MediHelp also lists interactions of Nimodipine with, for example, Apalutamide, Carbamazepine, Ceritinib. The full list is on the Nimodipine page.
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