Drug interactions
Dutasteride-tamsulosin + Oxymetazoline
Severity: Minor
Dutasteride-tamsulosin and Oxymetazoline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxymetazoline is an alpha-agonist vasoconstrictor that pharmacologically opposes tamsulosin. With topical nasal use, systemic absorption is low and the effect is usually negligible.
What this interaction means in plain words
Dutasteride-tamsulosin and Oxymetazoline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dutasteride-tamsulosin belongs to Genitourinary; Oxymetazoline belongs to Respiratory.
Why it happens
Pharmacodynamic antagonism between alpha-adrenergic agonism and alpha-1 blockade.
What to do
No action is needed for short-term nasal use; avoid exceeding recommended dosing.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dutasteride-tamsulosin
Other interactions of Oxymetazoline
- Isocarboxazid + Oxymetazoline Major
- Oxymetazoline + Phenelzine Major
- Oxymetazoline + Tranylcypromine Major
- Amitriptyline + Oxymetazoline Moderate
- Amoxapine + Oxymetazoline Moderate
- Clomipramine + Oxymetazoline Moderate
Frequently asked questions
Can I take Dutasteride-tamsulosin with Oxymetazoline?
MediHelp rates the interaction as minor. Dutasteride-tamsulosin and Oxymetazoline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oxymetazoline is an alpha-agonist vasoconstrictor that pharmacologically opposes tamsulosin. With topical nasal use, systemic absorption is low and the effect is usually negligible.
How serious is the interaction between Dutasteride-tamsulosin and Oxymetazoline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for short-term nasal use; avoid exceeding recommended dosing.
What other medicines interact with Dutasteride-tamsulosin?
MediHelp also lists interactions of Dutasteride-tamsulosin with, for example, Alfuzosin, Amifostine, Atazanavir. The full list is on the Dutasteride-tamsulosin page.
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