Drug interactions
Dutasteride-tamsulosin + Pyrimethamine
Severity: Minor
Dutasteride-tamsulosin and Pyrimethamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pyrimethamine has been reported to inhibit CYP2D6 in vitro but clinical relevance for tamsulosin is not established. Any effect is likely small.
What this interaction means in plain words
Dutasteride-tamsulosin and Pyrimethamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dutasteride-tamsulosin belongs to Genitourinary; Pyrimethamine belongs to Anti Parasitic.
Why it happens
Possible weak CYP2D6 inhibition; not clinically established.
What to do
No routine adjustment needed; monitor for dizziness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dutasteride-tamsulosin
Other interactions of Pyrimethamine
- Deferiprone + Pyrimethamine Major
- Eliglustat + Pyrimethamine Major
- Acalabrutinib + Pyrimethamine Moderate
- Brexpiprazole + Pyrimethamine Moderate
- Dapsone + Pyrimethamine Moderate
- Folic acid + Pyrimethamine Moderate
Frequently asked questions
Can I take Dutasteride-tamsulosin with Pyrimethamine?
MediHelp rates the interaction as minor. Dutasteride-tamsulosin and Pyrimethamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pyrimethamine has been reported to inhibit CYP2D6 in vitro but clinical relevance for tamsulosin is not established. Any effect is likely small.
How serious is the interaction between Dutasteride-tamsulosin and Pyrimethamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment needed; monitor for dizziness.
What other medicines interact with Dutasteride-tamsulosin?
MediHelp also lists interactions of Dutasteride-tamsulosin with, for example, Alfuzosin, Amifostine, Atazanavir. The full list is on the Dutasteride-tamsulosin page.
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