Drug interactions
Duvelisib + Pantoprazole
Severity: Minor
Duvelisib and Pantoprazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pantoprazole may inhibit BCRP and slightly raise duvelisib exposure, but this is not well established clinically. Any effect is likely small.
What this interaction means in plain words
Duvelisib and Pantoprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Duvelisib belongs to Oncology; Pantoprazole belongs to Gastrointestinal Tract.
Why it happens
Possible BCRP inhibition by pantoprazole increases duvelisib absorption.
What to do
No dose change is typically needed. Monitor for duvelisib toxicities such as diarrhea, rash and infection.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Pantoprazole
- Pantoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Pantoprazole Major
- Atazanavir + Pantoprazole Major
- Dacomitinib + Pantoprazole Major
- Dasatinib + Pantoprazole Major
- Erlotinib + Pantoprazole Major
Other interactions of Duvelisib
- Duvelisib + Ergotamine Contraindicated
- Alfuzosin + Duvelisib Major
- Apalutamide + Duvelisib Major
- Avanafil + Duvelisib Major
- Carbamazepine + Duvelisib Major
- Chloramphenicol + Duvelisib Major
Frequently asked questions
Can I take Duvelisib with Pantoprazole?
MediHelp rates the interaction as minor. Duvelisib and Pantoprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pantoprazole may inhibit BCRP and slightly raise duvelisib exposure, but this is not well established clinically. Any effect is likely small.
How serious is the interaction between Duvelisib and Pantoprazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is typically needed. Monitor for duvelisib toxicities such as diarrhea, rash and infection.
What other medicines interact with Pantoprazole?
MediHelp also lists interactions of Pantoprazole with, for example, Rilpivirine, Acalabrutinib, Atazanavir. The full list is on the Pantoprazole page.
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