Drug interactions
Echinacea + Mycophenolate mofetil
Severity: Moderate
Echinacea and Mycophenolate mofetil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Echinacea is reputed to stimulate the immune system and might counteract the effect of mycophenolate. Clinical data are lacking, and the concern is theoretical.
What this interaction means in plain words
Echinacea and Mycophenolate mofetil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Echinacea belongs to Gastrointestinal Tract; Mycophenolate mofetil belongs to Miscellaneous.
Why it happens
Theoretical pharmacodynamic opposition from immune stimulation by echinacea; no established mechanism.
What to do
Advise transplant and autoimmune patients to avoid echinacea products. Monitor for rejection or disease flare if the patient has used them.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
Other interactions of Echinacea
- Alefacept + Echinacea Moderate
- Antithymocyte globulin equine + Echinacea Moderate
- Antithymocyte globulin rabbit + Echinacea Moderate
- Azathioprine + Echinacea Moderate
- Basiliximab + Echinacea Moderate
- Cyclosporine + Echinacea Moderate
Frequently asked questions
Can I take Echinacea with Mycophenolate mofetil?
MediHelp rates the interaction as moderate. Echinacea and Mycophenolate mofetil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Echinacea is reputed to stimulate the immune system and might counteract the effect of mycophenolate. Clinical data are lacking, and the concern is theoretical.
How serious is the interaction between Echinacea and Mycophenolate mofetil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise transplant and autoimmune patients to avoid echinacea products. Monitor for rejection or disease flare if the patient has used them.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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