Drug interactions
Measles mumps and rubella vaccine live + Mycophenolate mofetil
Severity: Contraindicated
Measles mumps and rubella vaccine live and Mycophenolate mofetil: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
MMR is a live attenuated vaccine and may cause disseminated infection in patients on mycophenolate. Immunosuppression can also reduce vaccine effectiveness.
What this interaction means in plain words
Measles mumps and rubella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Why it happens
Immunosuppression impairs control of live attenuated viral replication.
What to do
Do not give while on mycophenolate. Vaccinate at least 4 weeks before starting therapy where possible, and ensure household contacts are immunised.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
- Mycophenolate mofetil + Rotavirus oral vaccine live Contraindicated
Frequently asked questions
Can I take Measles mumps and rubella vaccine live with Mycophenolate mofetil?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMR is a live attenuated vaccine and may cause disseminated infection in patients on mycophenolate. Immunosuppression can also reduce vaccine effectiveness.
How serious is the interaction between Measles mumps and rubella vaccine live and Mycophenolate mofetil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give while on mycophenolate. Vaccinate at least 4 weeks before starting therapy where possible, and ensure household contacts are immunised.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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