Drug interactions
Empagliflozin-linagliptin + Letermovir
Severity: Minor
Empagliflozin-linagliptin and Letermovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Letermovir inhibits OATP1B1/3 and may modestly raise exposure to some co-administered drugs, but the effect on empagliflozin is not well established. A clinically significant change in glucose-lowering is not expected.
What this interaction means in plain words
Empagliflozin-linagliptin and Letermovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Empagliflozin-linagliptin belongs to Endocrine; Letermovir belongs to Anti Virals.
Why it happens
Mechanism not firmly established; possible transporter inhibition by letermovir may modestly raise empagliflozin exposure.
What to do
No dose adjustment is needed; monitor blood glucose during co-administration.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Empagliflozin-linagliptin
Other interactions of Letermovir
- Ergotamine + Letermovir Contraindicated
- Letermovir + Pimozide Contraindicated
- Apalutamide + Letermovir Major
- Atorvastatin + Letermovir Major
- Carbamazepine + Letermovir Major
- Colchicine + Letermovir Major
Frequently asked questions
Can I take Empagliflozin-linagliptin with Letermovir?
MediHelp rates the interaction as minor. Empagliflozin-linagliptin and Letermovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Letermovir inhibits OATP1B1/3 and may modestly raise exposure to some co-administered drugs, but the effect on empagliflozin is not well established. A clinically significant change in glucose-lowering is not expected.
How serious is the interaction between Empagliflozin-linagliptin and Letermovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor blood glucose during co-administration.
What other medicines interact with Empagliflozin-linagliptin?
MediHelp also lists interactions of Empagliflozin-linagliptin with, for example, Fosphenytoin, Rifampin, Rifapentine. The full list is on the Empagliflozin-linagliptin page.
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