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Drug interactions

Empagliflozin-linagliptin + Tecovirimat

Severity: Minor

Empagliflozin-linagliptin and Tecovirimat: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Tecovirimat is a weak CYP3A4 inducer and may slightly lower linagliptin concentrations. The effect is expected to be small and temporary given the short treatment course.

What this interaction means in plain words

Empagliflozin-linagliptin and Tecovirimat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Empagliflozin-linagliptin belongs to Endocrine; Tecovirimat belongs to Miscellaneous.

Evidence level: Low

Why it happens

Weak induction of CYP3A4 increases linagliptin metabolism.

What to do

No dose change is needed; check blood glucose if control appears to worsen during treatment.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Empagliflozin-linagliptin with Tecovirimat?

MediHelp rates the interaction as minor. Empagliflozin-linagliptin and Tecovirimat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tecovirimat is a weak CYP3A4 inducer and may slightly lower linagliptin concentrations. The effect is expected to be small and temporary given the short treatment course.

How serious is the interaction between Empagliflozin-linagliptin and Tecovirimat?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; check blood glucose if control appears to worsen during treatment.

What other medicines interact with Empagliflozin-linagliptin?

MediHelp also lists interactions of Empagliflozin-linagliptin with, for example, Fosphenytoin, Rifampin, Rifapentine. The full list is on the Empagliflozin-linagliptin page.

Full monographs, dosing and an interaction checker in the MediHelp app

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