Drug interactions
Empagliflozin-metformin + Felodipine
Severity: Minor
Empagliflozin-metformin and Felodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dihydropyridine calcium channel blockers like felodipine have been reported to cause small increases in blood glucose in some patients. The effect is generally minor and rarely changes diabetes management.
What this interaction means in plain words
Empagliflozin-metformin and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Empagliflozin-metformin belongs to Endocrine; Felodipine belongs to Cardiovascular.
Why it happens
Calcium channel blockade may modestly reduce insulin release, but the mechanism is not firmly established.
What to do
No routine change is needed. Monitor glucose when felodipine is started or stopped and adjust therapy if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Empagliflozin-metformin
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Empagliflozin-metformin with Felodipine?
MediHelp rates the interaction as minor. Empagliflozin-metformin and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dihydropyridine calcium channel blockers like felodipine have been reported to cause small increases in blood glucose in some patients. The effect is generally minor and rarely changes diabetes management.
How serious is the interaction between Empagliflozin-metformin and Felodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor glucose when felodipine is started or stopped and adjust therapy if control changes.
What other medicines interact with Empagliflozin-metformin?
MediHelp also lists interactions of Empagliflozin-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Empagliflozin-metformin page.
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