Drug interactions
Emtricitabine + Meloxicam
Severity: Moderate
Emtricitabine and Meloxicam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are eliminated by the kidney, and NSAIDs can reduce renal function, which may raise emtricitabine exposure. The concern is greater with high or multiple NSAID doses and in patients with pre-existing renal impairment.
What this interaction means in plain words
Emtricitabine and Meloxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Emtricitabine belongs to Anti Virals; Meloxicam belongs to Musculoskeletal.
Why it happens
NSAID-related reduction in glomerular filtration and possible competition for tubular secretion reduce emtricitabine clearance.
What to do
Monitor renal function in patients taking meloxicam long term with emtricitabine, particularly if tenofovir is also used. Consider acetaminophen as an alternative.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Meloxicam
- Ketorolac intranasal + Meloxicam Contraindicated
- Ketorolac + Meloxicam Contraindicated
- Aceclofenac + Meloxicam Major
- Acemetacin + Meloxicam Major
- Acetylsalicylic acid + Meloxicam Major
- Alteplase + Meloxicam Major
Other interactions of Emtricitabine
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Emtricitabine Contraindicated
- Atidarsagene autotemcel + Emtricitabine Major
- Betibeglogene autotemcel + Emtricitabine Major
- Elivaldogene autotemcel + Emtricitabine Major
- Emtricitabine + Lamivudine Major
- Emtricitabine + Lovotibeglogene autotemcel Major
Frequently asked questions
Can I take Emtricitabine with Meloxicam?
MediHelp rates the interaction as moderate. Emtricitabine and Meloxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are eliminated by the kidney, and NSAIDs can reduce renal function, which may raise emtricitabine exposure. The concern is greater with high or multiple NSAID doses and in patients with pre-existing renal impairment.
How serious is the interaction between Emtricitabine and Meloxicam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function in patients taking meloxicam long term with emtricitabine, particularly if tenofovir is also used. Consider acetaminophen as an alternative.
What other medicines interact with Meloxicam?
MediHelp also lists interactions of Meloxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meloxicam page.
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