Drug interactions
Emtricitabine + Ublituximab
Severity: Moderate
Emtricitabine and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ublituximab depletes B cells and increases infection risk in a patient with HIV. It does not reduce emtricitabine activity, but patients on emtricitabine often also have hepatitis B, which can reactivate.
What this interaction means in plain words
Emtricitabine and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Emtricitabine belongs to Anti Virals; Ublituximab belongs to Miscellaneous.
Why it happens
Additive immunosuppression; no direct pharmacokinetic effect on emtricitabine.
What to do
Screen for hepatitis B before ublituximab. Monitor HBV markers, viral load and infections, and avoid stopping emtricitabine abruptly in HBV-coinfected patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Emtricitabine
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Emtricitabine Contraindicated
- Atidarsagene autotemcel + Emtricitabine Major
- Betibeglogene autotemcel + Emtricitabine Major
- Elivaldogene autotemcel + Emtricitabine Major
- Emtricitabine + Lamivudine Major
- Emtricitabine + Lovotibeglogene autotemcel Major
Other interactions of Ublituximab
Frequently asked questions
Can I take Emtricitabine with Ublituximab?
MediHelp rates the interaction as moderate. Emtricitabine and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ublituximab depletes B cells and increases infection risk in a patient with HIV. It does not reduce emtricitabine activity, but patients on emtricitabine often also have hepatitis B, which can reactivate.
How serious is the interaction between Emtricitabine and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Screen for hepatitis B before ublituximab. Monitor HBV markers, viral load and infections, and avoid stopping emtricitabine abruptly in HBV-coinfected patients.
What other medicines interact with Emtricitabine?
MediHelp also lists interactions of Emtricitabine with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Atidarsagene autotemcel, Betibeglogene autotemcel. The full list is on the Emtricitabine page.
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