Drug interactions
Emtricitabine + Valganciclovir
Severity: Moderate
Emtricitabine and Valganciclovir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are renally eliminated, and ganciclovir (from valganciclovir) may add hematologic toxicity. The pharmacokinetic effect is usually small with normal renal function.
What this interaction means in plain words
Emtricitabine and Valganciclovir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Emtricitabine belongs to Anti Virals; Valganciclovir belongs to Anti Virals.
Why it happens
Competition for renal tubular secretion plus additive hematologic toxicity.
What to do
Monitor blood counts and renal function, and adjust doses of both drugs when creatinine clearance is reduced.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Valganciclovir
Other interactions of Emtricitabine
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Emtricitabine Contraindicated
- Atidarsagene autotemcel + Emtricitabine Major
- Betibeglogene autotemcel + Emtricitabine Major
- Elivaldogene autotemcel + Emtricitabine Major
- Emtricitabine + Lamivudine Major
- Emtricitabine + Lovotibeglogene autotemcel Major
Frequently asked questions
Can I take Emtricitabine with Valganciclovir?
MediHelp rates the interaction as moderate. Emtricitabine and Valganciclovir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are renally eliminated, and ganciclovir (from valganciclovir) may add hematologic toxicity. The pharmacokinetic effect is usually small with normal renal function.
How serious is the interaction between Emtricitabine and Valganciclovir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and renal function, and adjust doses of both drugs when creatinine clearance is reduced.
What other medicines interact with Valganciclovir?
MediHelp also lists interactions of Valganciclovir with, for example, Didanosine, Ganciclovir, Liposomal doxorubicin. The full list is on the Valganciclovir page.
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