Drug interactions
Enalapril-hydrochlorothiazide + Ferrous gluconate
Severity: Minor
Enalapril-hydrochlorothiazide and Ferrous gluconate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral iron has been rarely reported to cause hypotension and gastrointestinal symptoms when given with ACE inhibitors, but the evidence is limited. Intravenous iron has a better-described reaction risk, but this pair concerns oral iron.
What this interaction means in plain words
Enalapril-hydrochlorothiazide and Ferrous gluconate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Enalapril-hydrochlorothiazide belongs to Cardiovascular; Ferrous gluconate belongs to Miscellaneous.
Why it happens
Mechanism is not established.
What to do
No dose change is needed. Monitor blood pressure if symptoms such as dizziness occur after starting iron.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Enalapril-hydrochlorothiazide
- Aliskiren + Enalapril-hydrochlorothiazide Contraindicated
- Dofetilide + Enalapril-hydrochlorothiazide Contraindicated
- Enalapril-hydrochlorothiazide + Protein a column Contraindicated
- Enalapril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Amifostine + Enalapril-hydrochlorothiazide Major
- Amiloride + Enalapril-hydrochlorothiazide Major
Other interactions of Ferrous gluconate
Frequently asked questions
Can I take Enalapril-hydrochlorothiazide with Ferrous gluconate?
MediHelp rates the interaction as minor. Enalapril-hydrochlorothiazide and Ferrous gluconate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral iron has been rarely reported to cause hypotension and gastrointestinal symptoms when given with ACE inhibitors, but the evidence is limited. Intravenous iron has a better-described reaction risk, but this pair concerns oral iron.
How serious is the interaction between Enalapril-hydrochlorothiazide and Ferrous gluconate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Monitor blood pressure if symptoms such as dizziness occur after starting iron.
What other medicines interact with Enalapril-hydrochlorothiazide?
MediHelp also lists interactions of Enalapril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Enalapril-hydrochlorothiazide page.
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