Drug interactions
Eprosartan-hydrochlorothiazide + Nadolol
Severity: Minor
Eprosartan-hydrochlorothiazide and Nadolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nadolol and the eprosartan-hydrochlorothiazide combination both lower blood pressure, so additive hypotension and bradycardia are possible. The combination is common in practice and generally manageable. Thiazides may modestly affect glucose and lipids.
What this interaction means in plain words
Eprosartan-hydrochlorothiazide and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Eprosartan-hydrochlorothiazide belongs to Cardiovascular; Nadolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects through beta-blockade, angiotensin receptor blockade and diuresis.
What to do
Monitor blood pressure and heart rate when starting or titrating. Adjust doses if symptomatic hypotension or bradycardia develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Nadolol
Frequently asked questions
Can I take Eprosartan-hydrochlorothiazide with Nadolol?
MediHelp rates the interaction as minor. Eprosartan-hydrochlorothiazide and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nadolol and the eprosartan-hydrochlorothiazide combination both lower blood pressure, so additive hypotension and bradycardia are possible. The combination is common in practice and generally manageable. Thiazides may modestly affect glucose and lipids.
How serious is the interaction between Eprosartan-hydrochlorothiazide and Nadolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or titrating. Adjust doses if symptomatic hypotension or bradycardia develops.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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