Drug interactions
Eprosartan-hydrochlorothiazide + Nebivolol
Severity: Minor
Eprosartan-hydrochlorothiazide and Nebivolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nebivolol adds to the blood pressure lowering effect of the eprosartan-hydrochlorothiazide combination. This may cause excessive hypotension or bradycardia, though the combination is commonly used therapeutically.
What this interaction means in plain words
Eprosartan-hydrochlorothiazide and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Eprosartan-hydrochlorothiazide belongs to Cardiovascular; Nebivolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects through beta-blockade, angiotensin receptor blockade and diuresis.
What to do
Monitor blood pressure and heart rate during initiation and dose changes. Reduce doses if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Eprosartan-hydrochlorothiazide with Nebivolol?
MediHelp rates the interaction as minor. Eprosartan-hydrochlorothiazide and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nebivolol adds to the blood pressure lowering effect of the eprosartan-hydrochlorothiazide combination. This may cause excessive hypotension or bradycardia, though the combination is commonly used therapeutically.
How serious is the interaction between Eprosartan-hydrochlorothiazide and Nebivolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during initiation and dose changes. Reduce doses if symptomatic hypotension occurs.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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