Drug interactions
Ergoloid mesylates + Lurasidone
Severity: Minor
Ergoloid mesylates and Lurasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ergoloid mesylates have dopaminergic and serotonergic activity, so combining them with an antipsychotic could in theory alter the response to both drugs. Serotonin toxicity or neuroleptic malignant syndrome is theoretical, with little clinical evidence.
What this interaction means in plain words
Ergoloid mesylates and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic overlap at dopamine and serotonin receptors; the mechanism is not established.
What to do
No routine change is needed. Watch for new fever, rigidity, agitation or autonomic instability and review therapy if these appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Frequently asked questions
Can I take Ergoloid mesylates with Lurasidone?
MediHelp rates the interaction as minor. Ergoloid mesylates and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ergoloid mesylates have dopaminergic and serotonergic activity, so combining them with an antipsychotic could in theory alter the response to both drugs. Serotonin toxicity or neuroleptic malignant syndrome is theoretical, with little clinical evidence.
How serious is the interaction between Ergoloid mesylates and Lurasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Watch for new fever, rigidity, agitation or autonomic instability and review therapy if these appear.
What other medicines interact with Lurasidone?
MediHelp also lists interactions of Lurasidone with, for example, Apalutamide, Atazanavir, Carbamazepine. The full list is on the Lurasidone page.
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