Drug interactions
Ergoloid mesylates + Nitroglycerin
Severity: Minor
Ergoloid mesylates and Nitroglycerin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ergoloid mesylates are dihydrogenated ergot derivatives with far weaker vasoconstrictor activity than other ergots. Meaningful antagonism of nitroglycerin is not well documented.
What this interaction means in plain words
Ergoloid mesylates and Nitroglycerin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical opposing vascular effects; not established for ergoloid mesylates.
What to do
No specific action is needed beyond monitoring angina control and blood pressure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nitroglycerin
- Avanafil + Nitroglycerin Contraindicated
- Nitroglycerin + Riociguat Contraindicated
- Nitroglycerin + Sildenafil Contraindicated
- Nitroglycerin + Tadalafil Contraindicated
- Nitroglycerin + Vardenafil Contraindicated
- Dihydroergotamine intranasal + Nitroglycerin Major
Frequently asked questions
Can I take Ergoloid mesylates with Nitroglycerin?
MediHelp rates the interaction as minor. Ergoloid mesylates and Nitroglycerin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ergoloid mesylates are dihydrogenated ergot derivatives with far weaker vasoconstrictor activity than other ergots. Meaningful antagonism of nitroglycerin is not well documented.
How serious is the interaction between Ergoloid mesylates and Nitroglycerin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond monitoring angina control and blood pressure.
What other medicines interact with Nitroglycerin?
MediHelp also lists interactions of Nitroglycerin with, for example, Avanafil, Riociguat, Sildenafil. The full list is on the Nitroglycerin page.
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