Drug interactions
Erythromycin + Tinidazole
Severity: Minor
Erythromycin and Tinidazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tinidazole is partly metabolized by CYP3A4, so erythromycin could modestly raise its levels. No significant clinical consequence is documented.
What this interaction means in plain words
Erythromycin and Tinidazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Erythromycin belongs to Anti Bacterial; Tinidazole belongs to Anti Parasitic.
Why it happens
Possible CYP3A4 inhibition by erythromycin reducing tinidazole metabolism.
What to do
No adjustment is generally needed; monitor for gastrointestinal or neurological adverse effects of tinidazole.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Erythromycin
- Conivaptan + Erythromycin Contraindicated
- Dihydroergotamine intranasal + Erythromycin Contraindicated
- Dihydroergotamine + Erythromycin Contraindicated
- Domperidone + Erythromycin Contraindicated
- Dronedarone + Erythromycin Contraindicated
- Droperidol + Erythromycin Contraindicated
Other interactions of Tinidazole
- Disulfiram + Tinidazole Contraindicated
- Ethanol + Tinidazole Major
- Fexinidazole + Tinidazole Major
- Lopinavir + Tinidazole Major
- Nilotinib + Tinidazole Major
- Ritonavir + Tinidazole Major
Frequently asked questions
Can I take Erythromycin with Tinidazole?
MediHelp rates the interaction as minor. Erythromycin and Tinidazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tinidazole is partly metabolized by CYP3A4, so erythromycin could modestly raise its levels. No significant clinical consequence is documented.
How serious is the interaction between Erythromycin and Tinidazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No adjustment is generally needed; monitor for gastrointestinal or neurological adverse effects of tinidazole.
What other medicines interact with Erythromycin?
MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.
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