Drug interactions
Erythromycin ethylsuccinate + Eslicarbazepine
Severity: Minor
Erythromycin ethylsuccinate and Eslicarbazepine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eslicarbazepine may reduce erythromycin concentrations through CYP3A4 induction. This could reduce antibacterial efficacy, though the effect is likely modest.
What this interaction means in plain words
Erythromycin ethylsuccinate and Eslicarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
CYP3A4 induction by eslicarbazepine increases erythromycin metabolism.
What to do
Monitor clinical response to the infection and consider an alternative antibiotic if treatment fails.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eslicarbazepine
- Eslicarbazepine + Mavacamten Contraindicated
- Eslicarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Eslicarbazepine Major
- Avapritinib + Eslicarbazepine Major
- Bedaquiline + Eslicarbazepine Major
- Benzhydrocodone / acetaminophen + Eslicarbazepine Major
Frequently asked questions
Can I take Erythromycin ethylsuccinate with Eslicarbazepine?
MediHelp rates the interaction as minor. Erythromycin ethylsuccinate and Eslicarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eslicarbazepine may reduce erythromycin concentrations through CYP3A4 induction. This could reduce antibacterial efficacy, though the effect is likely modest.
How serious is the interaction between Erythromycin ethylsuccinate and Eslicarbazepine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to the infection and consider an alternative antibiotic if treatment fails.
What other medicines interact with Eslicarbazepine?
MediHelp also lists interactions of Eslicarbazepine with, for example, Mavacamten, Rilpivirine, Artemether / lumefantrine. The full list is on the Eslicarbazepine page.
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