Drug interactions
Escitalopram + Indacaterol-glycopyrronium
Severity: Moderate
Escitalopram and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Escitalopram causes dose-related QT prolongation, and indacaterol may modestly affect repolarization. The combination could increase the risk of arrhythmia, especially with electrolyte disturbances or other risk factors.
What this interaction means in plain words
Escitalopram and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Escitalopram belongs to Central Nervous System; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Additive effects on cardiac repolarization.
What to do
Keep escitalopram at the lowest effective dose and correct potassium and magnesium. Obtain an ECG if the patient has cardiac risk factors or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Escitalopram
- Cisapride + Escitalopram Contraindicated
- Citalopram + Escitalopram Contraindicated
- Escitalopram + Isocarboxazid Contraindicated
- Escitalopram + Methylene blue Contraindicated
- Escitalopram + Phenelzine Contraindicated
- Escitalopram + Pimozide Contraindicated
Frequently asked questions
Can I take Escitalopram with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Escitalopram and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Escitalopram causes dose-related QT prolongation, and indacaterol may modestly affect repolarization. The combination could increase the risk of arrhythmia, especially with electrolyte disturbances or other risk factors.
How serious is the interaction between Escitalopram and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Keep escitalopram at the lowest effective dose and correct potassium and magnesium. Obtain an ECG if the patient has cardiac risk factors or other QT-prolonging drugs.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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