Drug interactions
Esmolol + Formoterol
Severity: Moderate
Esmolol and Formoterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Esmolol blocks beta-1 receptors and can oppose the bronchodilating action of formoterol, particularly at higher doses or in patients with reactive airways. The practical effect is usually small because esmolol is cardioselective and short-acting.
What this interaction means in plain words
Esmolol and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Esmolol belongs to Cardiovascular; Formoterol belongs to Respiratory.
Why it happens
Pharmacodynamic antagonism at beta-adrenergic receptors, with loss of selectivity at higher esmolol doses.
What to do
Monitor respiratory status and wheeze in patients with asthma or COPD during esmolol infusion. Reduce the esmolol dose or stop it if bronchospasm develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Esmolol
- Acebutolol + Esmolol Major
- Amifostine + Esmolol Major
- Amiodarone + Esmolol Major
- Celiprolol + Esmolol Major
- Diltiazem + Esmolol Major
- Epinephrine racemic + Esmolol Major
Frequently asked questions
Can I take Esmolol with Formoterol?
MediHelp rates the interaction as moderate. Esmolol and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Esmolol blocks beta-1 receptors and can oppose the bronchodilating action of formoterol, particularly at higher doses or in patients with reactive airways. The practical effect is usually small because esmolol is cardioselective and short-acting.
How serious is the interaction between Esmolol and Formoterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory status and wheeze in patients with asthma or COPD during esmolol infusion. Reduce the esmolol dose or stop it if bronchospasm develops.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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