Drug interactions
Esmolol + Glucagon intranasal
Severity: Minor
Esmolol and Glucagon intranasal: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon can transiently raise heart rate and blood pressure, which may be seen in patients taking beta-blockers. This is mostly relevant when glucagon is used to treat hypoglycemia, and beta-blockade can also mask hypoglycemia symptoms.
What this interaction means in plain words
Esmolol and Glucagon intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Glucagon raises catecholamine release and cardiac stimulation, partly counteracting beta-blockade, while beta-blockers mask adrenergic hypoglycemia signs.
What to do
Monitor blood pressure and pulse after glucagon administration and check blood glucose rather than relying on symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Esmolol
- Acebutolol + Esmolol Major
- Amifostine + Esmolol Major
- Amiodarone + Esmolol Major
- Celiprolol + Esmolol Major
- Diltiazem + Esmolol Major
- Epinephrine racemic + Esmolol Major
Frequently asked questions
Can I take Esmolol with Glucagon intranasal?
MediHelp rates the interaction as minor. Esmolol and Glucagon intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucagon can transiently raise heart rate and blood pressure, which may be seen in patients taking beta-blockers. This is mostly relevant when glucagon is used to treat hypoglycemia, and beta-blockade can also mask hypoglycemia symptoms.
How serious is the interaction between Esmolol and Glucagon intranasal?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and pulse after glucagon administration and check blood glucose rather than relying on symptoms.
What other medicines interact with Esmolol?
MediHelp also lists interactions of Esmolol with, for example, Acebutolol, Amifostine, Amiodarone. The full list is on the Esmolol page.
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