Drug interactions
Esmolol + Metipranolol
Severity: Minor
Esmolol and Metipranolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ophthalmic metipranolol is systemically absorbed to some degree and may add to the beta-blockade of esmolol. This can cause additive bradycardia or hypotension.
What this interaction means in plain words
Esmolol and Metipranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive beta-adrenergic blockade.
What to do
Monitor heart rate and blood pressure during esmolol infusion in patients using the eye drops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Esmolol
- Acebutolol + Esmolol Major
- Amifostine + Esmolol Major
- Amiodarone + Esmolol Major
- Celiprolol + Esmolol Major
- Diltiazem + Esmolol Major
- Epinephrine racemic + Esmolol Major
Frequently asked questions
Can I take Esmolol with Metipranolol?
MediHelp rates the interaction as minor. Esmolol and Metipranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ophthalmic metipranolol is systemically absorbed to some degree and may add to the beta-blockade of esmolol. This can cause additive bradycardia or hypotension.
How serious is the interaction between Esmolol and Metipranolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure during esmolol infusion in patients using the eye drops.
What other medicines interact with Esmolol?
MediHelp also lists interactions of Esmolol with, for example, Acebutolol, Amifostine, Amiodarone. The full list is on the Esmolol page.
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