Drug interactions
Esmolol + Olmesartan
Severity: Minor
Esmolol and Olmesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Esmolol and olmesartan together have additive antihypertensive effects, which is usually desirable but can lead to hypotension. Both drugs can also modestly raise serum potassium, beta-blockers by impairing cellular uptake and ARBs by reducing aldosterone.
What this interaction means in plain words
Esmolol and Olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Esmolol belongs to Cardiovascular; Olmesartan belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering, with small additive potassium-raising effects from beta blockade and angiotensin receptor blockade.
What to do
Monitor blood pressure and serum potassium, especially in renal impairment or with other potassium-raising drugs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Esmolol
- Acebutolol + Esmolol Major
- Amifostine + Esmolol Major
- Amiodarone + Esmolol Major
- Celiprolol + Esmolol Major
- Diltiazem + Esmolol Major
- Epinephrine racemic + Esmolol Major
Other interactions of Olmesartan
- Aliskiren + Olmesartan Contraindicated
- Olmesartan + Sparsentan Contraindicated
- Aldesleukin + Olmesartan Major
- Amifostine + Olmesartan Major
- Amiloride + Olmesartan Major
- Amlodipine-benazepril + Olmesartan Major
Frequently asked questions
Can I take Esmolol with Olmesartan?
MediHelp rates the interaction as minor. Esmolol and Olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Esmolol and olmesartan together have additive antihypertensive effects, which is usually desirable but can lead to hypotension. Both drugs can also modestly raise serum potassium, beta-blockers by impairing cellular uptake and ARBs by reducing aldosterone.
How serious is the interaction between Esmolol and Olmesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and serum potassium, especially in renal impairment or with other potassium-raising drugs.
What other medicines interact with Esmolol?
MediHelp also lists interactions of Esmolol with, for example, Acebutolol, Amifostine, Amiodarone. The full list is on the Esmolol page.
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