Drug interactions
Estrogens conjugated synthetic + Moxifloxacin
Severity: Minor
Estrogens conjugated synthetic and Moxifloxacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
A reduction in oral estrogen levels through antibiotic effects on gut flora has been proposed but not shown for fluoroquinolones. Clinically significant loss of estrogen effect is not expected.
What this interaction means in plain words
Estrogens conjugated synthetic and Moxifloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical decrease in enterohepatic recirculation of estrogen from altered gut flora, not demonstrated for moxifloxacin.
What to do
No dose adjustment is needed. Reassess only if symptoms of estrogen deficiency or breakthrough bleeding occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Estrogens conjugated synthetic with Moxifloxacin?
MediHelp rates the interaction as minor. Estrogens conjugated synthetic and Moxifloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. A reduction in oral estrogen levels through antibiotic effects on gut flora has been proposed but not shown for fluoroquinolones. Clinically significant loss of estrogen effect is not expected.
How serious is the interaction between Estrogens conjugated synthetic and Moxifloxacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. Reassess only if symptoms of estrogen deficiency or breakthrough bleeding occur.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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